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子痫前期与父系变更

Pre-eclampsia and changed paternity.

作者信息

Feeney J G, Scott J S

出版信息

Eur J Obstet Gynecol Reprod Biol. 1980 Sep;11(1):35-8. doi: 10.1016/0028-2243(80)90051-9.

DOI:10.1016/0028-2243(80)90051-9
PMID:7193608
Abstract

A review of 34, 201 multigravid deliveries found 47 patients who had severe pre-eclampsia after previous normotensive, non-albuminuric pregnancies. In 13 of these patients the affected pregnancy was apparently by a new father compared with 3 matched controls (P less than 0.01). This evidence supports the idea of a paternal immunogenetic factor in pre-eclampsia; immunogenetics.

摘要

对34201例多胎分娩的回顾发现,有47例患者在既往血压正常、无蛋白尿的妊娠后发生了重度子痫前期。在这些患者中,有13例此次受影响的妊娠明显是与新的父亲有关,而3例匹配的对照组则不然(P<0.01)。这一证据支持了子痫前期存在父系免疫遗传因素的观点;免疫遗传学。

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