Léonard A, Decat G, Maisin J R
C R Seances Soc Biol Fil. 1977;171(3):682-5.
G-banded karyotypes have been studied in C57Bl control mice and in animals developing leukemia after i.p. injection of acellular extract of spleen or lymph nodes from isologous animals showing radiation induced leukemia. No visible differences could be detected with respect to the number, size and position of the G-bands between the two groups of animals. From the present observations and from previous work with conventional staining methods, it can be concluded that the development of such leukemia does not involve the presence of chromosome abnormalities.
对C57Bl对照小鼠以及经腹腔注射来自显示辐射诱导白血病的同源动物的脾脏或淋巴结无细胞提取物后发生白血病的动物进行了G带核型研究。在两组动物之间,在G带的数量、大小和位置方面未检测到明显差异。根据目前的观察结果以及先前使用传统染色方法的研究工作,可以得出结论,这种白血病的发生不涉及染色体异常。