• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

绿唇贻贝(Perna canaliculus)制剂的胃保护和抗炎特性。

Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.

作者信息

Rainsford K D, Whitehouse M W

出版信息

Arzneimittelforschung. 1980;30(12):2128-32.

PMID:7194074
Abstract

Freeze-dried powdered preparations of whole (i.e. without shell) green-lipped mussel (Perna canaliculus) from New Zealand given orally to rats showed some modest anti-inflammatory activity (carrageenan paw oedema). This material strikingly reduced the gastric ulcerogenicity of several non-steroid anti-inflammatory drugs in rats and pigs. The gastroprotective activity in rats was primarily associated with particular lipid fractions, which exhibited differential protective activity against acetylsalicylic acid on the one hand and indometacin on the other.

摘要

给大鼠口服来自新西兰的冻干全(即无壳)绿唇贻贝(Perna canaliculus)粉末制剂,显示出一定程度的抗炎活性(角叉菜胶致爪肿胀)。该物质显著降低了几种非甾体抗炎药对大鼠和猪的致胃溃疡性。大鼠的胃保护活性主要与特定的脂质组分有关,这些脂质组分对乙酰水杨酸和吲哚美辛分别表现出不同的保护活性。

相似文献

1
Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.绿唇贻贝(Perna canaliculus)制剂的胃保护和抗炎特性。
Arzneimittelforschung. 1980;30(12):2128-32.
2
The anti-inflammatory activity of Perna canaliculus (NZ green lipped mussel).新西兰绿唇贻贝(Perna canaliculus)的抗炎活性。
N Z Med J. 1980 Sep 10;92(667):187-93.
3
Fatty acid and sterol composition of frozen and freeze-dried New Zealand Green Lipped Mussel (Perna canaliculus) from three sites in New Zealand.来自新西兰三个地点的冷冻和冻干新西兰绿唇贻贝(Perna canaliculus)的脂肪酸和甾醇组成。
Asia Pac J Clin Nutr. 2003;12(1):50-60.
4
Anti-cyclooxygenase effects of lipid extracts from the New Zealand green-lipped mussel, Perna canaliculus.新西兰绿唇贻贝(Perna canaliculus)脂质提取物的抗环氧化酶作用。
Comp Biochem Physiol B Biochem Mol Biol. 2007 Mar;146(3):346-56. doi: 10.1016/j.cbpb.2006.11.001. Epub 2006 Nov 17.
5
Anti-inflammatory activity in fractionated extracts of the green-lipped mussel.
N Z Med J. 1982 Nov 24;95(720):803-6.
6
Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus (Lyprinol).贻贝(Lyprinol)稳定脂质提取物的抗炎作用。
Allerg Immunol (Paris). 2000 Sep;32(7):272-8.
7
Perna canaliculus in the treatment of rheumatoid arthritis.
Eur J Rheumatol Inflamm. 1983;6(2):197-200.
8
Gastroprotective effect of simvastatin against indomethacin-induced gastric ulcer in rats: role of nitric oxide and prostaglandins.辛伐他汀对吲哚美辛诱导的大鼠胃溃疡的胃保护作用:一氧化氮和前列腺素的作用
Eur J Pharmacol. 2009 Apr 1;607(1-3):188-93. doi: 10.1016/j.ejphar.2009.02.008. Epub 2009 Feb 13.
9
The CO2-SFE crude lipid extract and the free fatty acid extract from Perna canaliculus have anti-inflammatory effects on adjuvant-induced arthritis in rats.贻贝的二氧化碳超临界流体萃取粗脂质提取物和游离脂肪酸提取物对佐剂诱导的大鼠关节炎具有抗炎作用。
Comp Biochem Physiol B Biochem Mol Biol. 2008 Feb;149(2):251-8. doi: 10.1016/j.cbpb.2007.09.015. Epub 2007 Sep 26.
10
Novel anti-inflammatory omega-3 PUFAs from the New Zealand green-lipped mussel, Perna canaliculus.来自新西兰绿唇贻贝(Perna canaliculus)的新型抗炎omega-3多不饱和脂肪酸。
Comp Biochem Physiol B Biochem Mol Biol. 2007 Aug;147(4):645-56. doi: 10.1016/j.cbpb.2007.04.004. Epub 2007 Apr 14.

引用本文的文献

1
Efficacy and Safety Assessment of a Dietary Supplement in a Rat Model of Osteoarthritis and Dogs with Arthritic Signs.一种膳食补充剂在骨关节炎大鼠模型和患有关节炎体征的犬类中的疗效与安全性评估。
Animals (Basel). 2025 Jun 20;15(13):1825. doi: 10.3390/ani15131825.
2
Perna canaliculus and the Intestinal Microbiome.绿唇贻贝与肠道微生物群
Mar Drugs. 2017 Jun 30;15(7):207. doi: 10.3390/md15070207.
3
Therapeutic Effect of Ficus lacor Aerial Roots of Various Fractions on Adjuvant-Induced Arthritic Rats.不同部位大果榕气生根对佐剂性关节炎大鼠的治疗作用
ISRN Pharmacol. 2013 Sep 17;2013:634106. doi: 10.1155/2013/634106. eCollection 2013.
4
Green-lipped mussel (Perna canaliculus) extract efficacy in knee osteoarthritis and improvement in gastrointestinal dysfunction: a pilot study.绿唇贻贝(Perna canaliculus)提取物对膝骨关节炎的疗效及对胃肠功能障碍的改善:一项初步研究。
Inflammopharmacology. 2012 Apr;20(2):71-6. doi: 10.1007/s10787-012-0128-6. Epub 2012 Feb 26.
5
Anti-inflammatory activities of aqueous/ethanol and methanol extracts of Perna viridis Linn. in mice.绿贻贝(Perna viridis Linn.)水/乙醇提取物和甲醇提取物对小鼠的抗炎活性。
Inflammopharmacology. 2011 Dec;19(6):335-41. doi: 10.1007/s10787-010-0075-z. Epub 2011 Feb 27.
6
Gastric cytoprotection 30 years after its discovery by André Robert: a personal perspective.胃黏膜细胞保护作用的发现 30 年后:个人视角。
Inflammopharmacology. 2010 Oct;18(5):209-21. doi: 10.1007/s10787-010-0045-5. Epub 2010 Jul 2.
7
Evaluating Complementary Therapies for Canine Osteoarthritis Part I: Green-lipped Mussel (Perna canaliculus).评估用于犬骨关节炎的补充疗法 第一部分:绿唇贻贝(Perna canaliculus)。
Evid Based Complement Alternat Med. 2009 Sep;6(3):365-73. doi: 10.1093/ecam/nem136. Epub 2007 Oct 29.
8
Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel.新西兰青口贻贝脂类(lyprinol)的抗炎活性。
Inflammopharmacology. 1997;5(3):237-46. doi: 10.1007/s10787-997-0002-0.
9
Non-NSAID over-the-counter (OTC) remedies for arthritis: good, bad or indifferent?非 NSAID 类关节炎 otc 药物:疗效如何?
Inflammopharmacology. 1999;7(3):227-47. doi: 10.1007/s10787-999-0006-z.
10
Systematic review of a marine nutriceutical supplement in clinical trials for arthritis: the effectiveness of the New Zealand green-lipped mussel Perna canaliculus.对一种用于关节炎临床试验的海洋营养补充剂的系统评价:新西兰绿唇贻贝(Perna canaliculus)的有效性。
Clin Rheumatol. 2006 May;25(3):275-84. doi: 10.1007/s10067-005-0001-8. Epub 2005 Oct 12.