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Fluid loading to reduce abnormalities of fetal heart rate and maternal hypotension during epidural analgesia in labour.在分娩时硬膜外镇痛期间进行液体输注以减少胎儿心率异常和产妇低血压。
Br Med J. 1978 Nov 25;2(6150):1460-1. doi: 10.1136/bmj.2.6150.1460.
2
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Maternal heart rate variability patterns associated with maternal hypotension and non-reassuring fetal heart rate patterns following initiation of combined spinal-epidural labor analgesia: a prospective observational trial.起始联合脊麻-硬膜外分娩镇痛后与产妇低血压和不令人安心的胎儿心率模式相关的母体心率变异性模式：一项前瞻性观察性试验。
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[Preloading with 500 ml of Hartmann's solution lessens the incidence and severity of hypotension and reduces the need for ephedrine after epidural anesthesia in ambulatory patients].对于门诊患者，硬膜外麻醉前预注500毫升哈特曼氏溶液可降低低血压的发生率和严重程度，并减少麻黄碱的使用需求。
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Changes in fetal TCPO2 values occurring during labour in association with lumbar extradural analgesia.分娩过程中与腰段硬膜外镇痛相关的胎儿经皮氧分压（TCPO2）值的变化。
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Epidural analgesia for childbirth: effects of newer techniques on neonatal outcome.分娩硬膜外镇痛：新技术对新生儿结局的影响。
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Haemodynamic consequences and uterine contractions following 0.5 or 1.0 litre crystalloid infusion before obstetric epidural analgesia.
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本文引用的文献

1
Acute hydration for prevention of hypotension of spinal anesthesia in parturients.急性补液预防产妇脊髓麻醉后低血压
Anesthesiology. 1968 Mar-Apr;29(2):374-80. doi: 10.1097/00000542-196803000-00024.
2
Biochemical status and clinical condition of mother and infant at cesarean section.剖宫产时母婴的生化状态及临床状况。
Anesth Analg. 1969 Nov-Dec;48(6):986-94.
3
Aortocaval compression during cesarean section. A cause of newborn depression.
Obstet Gynecol. 1971 May;37(5):702-5.
4
Lateral table tilt for Caesarean section.剖宫产术中的侧卧位手术台倾斜
Anaesthesia. 1974 Nov;29(6):696-703. doi: 10.1111/j.1365-2044.1974.tb00755.x.
5
Obstetric consequences of epidural analgesia in nulliparous patients.
Lancet. 1971 May 22;1(7708):1031-4. doi: 10.1016/s0140-6736(71)91602-3.
6
Posture and epidural block in pregnant women at term. Effects on arterial blood pressure and limb blood flow.足月孕妇的体位与硬膜外阻滞。对动脉血压和肢体血流的影响。
Anaesthesia. 1975 Nov;30(6):752-6. doi: 10.1111/j.1365-2044.1975.tb00950.x.
7
Prevention of spinal hypotension associated with Cesarean section.
Anesthesiology. 1976 Dec;45(6):670-4. doi: 10.1097/00000542-197612000-00018.
8
The fetal and neonatal effects of regional anesthesia in obstetrics.产科区域麻醉对胎儿和新生儿的影响。
Anesthesiology. 1978 Jan;48(1):34-64. doi: 10.1097/00000542-197801000-00007.
9
The aetiology, characteristics and diagnostic relevance of late deceleration patterns in routine obstetric practice.常规产科实践中晚期减速模式的病因、特征及诊断意义。
Br J Obstet Gynaecol. 1975 Feb;82(2):121-5. doi: 10.1111/j.1471-0528.1975.tb02208.x.
10
Epidural analgesia with left lateral tilt for Caesarean section.剖宫产术采用左侧卧位的硬膜外镇痛。
Anaesthesia. 1975 May;30(3):396-401. doi: 10.1111/j.1365-2044.1975.tb00874.x.

在分娩时硬膜外镇痛期间进行液体输注以减少胎儿心率异常和产妇低血压。

Fluid loading to reduce abnormalities of fetal heart rate and maternal hypotension during epidural analgesia in labour.

作者信息

Collins K M, Bevan D R, Beard R W

出版信息

Br Med J. 1978 Nov 25;2(6150):1460-1. doi: 10.1136/bmj.2.6150.1460.

DOI:10.1136/bmj.2.6150.1460
PMID:719463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1608676/
Abstract

Fetal heart rate (FHR) was recorded and maternal blood pressure measured in 104 patients in whom lumbar epidural analgesia was induced in labour. Fifty-one patients received an intravenous load of 11 of Hartmann's solution immediately before the epidural injection. This infusion significantly reduced the incidence of abnormalities of FHR from 34% to 12% and of maternal hypotension from 28% to 2%. We did not study mothers with pre-eclampsia and hypertension, but we conclude that there is a strong case for preloading all other mothers in whom lumbar epidural analgesia is induced in labour.

摘要

对104例分娩时接受腰段硬膜外镇痛的患者记录了胎心率（FHR）并测量了产妇血压。51例患者在硬膜外注射前立即静脉输注1升复方氯化钠溶液。这种输注显著降低了FHR异常的发生率，从34%降至12%，产妇低血压的发生率从28%降至2%。我们没有研究患有先兆子痫和高血压的母亲，但我们得出结论，对于所有其他分娩时接受腰段硬膜外镇痛的母亲，有充分的理由进行预负荷。