Patil R K, Sinha S N, Einarsson S, Settergren I
Nord Vet Med. 1980 Nov;32(11):474-9.
Uterine strips were collected from cows during the follicular and the luteal phases as well as from cows with ovarian cysts. The strips were mounted in organ baths and the motility was recorded by a polygraph. After the spontaneous motility of the strips had reached a steady state the test substances PGF2 alpha and oxytocin were added to the bath at three different concentrations. Frequency, amplitude and duration of the spontaneous uterine concentrations were irregular in all strips recorded independent of reproductive stage. The spontaneous activity was most pronounced during the follicular phase. The variation between animals was greatest for cystic cows. PGF2 alpha always increased the activity of the uterus but the response was not dose related above a certain level (50 ng per ml bath fluid). Oxytocin on the other hand had a linear stimulatory effect for increasing doses (0.25, 2.5 and 25 mIU per ml bath fluid).
在卵泡期、黄体期以及患有卵巢囊肿的奶牛中采集子宫肌条。将这些肌条安装在器官浴槽中,并用记录仪记录其运动情况。在肌条的自发运动达到稳定状态后,将三种不同浓度的测试物质前列腺素F2α(PGF2α)和催产素添加到浴槽中。在所有记录的肌条中,无论处于何种生殖阶段,子宫自发收缩的频率、幅度和持续时间都是不规则的。自发活动在卵泡期最为明显。患有囊肿的奶牛个体之间的差异最大。PGF2α总是会增加子宫的活动,但在超过一定水平(每毫升浴液50纳克)后,反应与剂量无关。另一方面,催产素对于增加的剂量(每毫升浴液0.25、2.5和25毫国际单位)具有线性刺激作用。