Schweppe K W, Möhlen K H, Beller F K
Z Geburtshilfe Perinatol. 1980 Feb;184(1):1-10.
The problems of medical, eugenic and social or psycho-social indication are discussed on the basis of the literature published during the past 40 years. Prognosis is not as unfavourable as generally assumed, especially during the lactation period. The processes of gestation have no clearly identifiable unfavourable influence on prognosis. On the contrary, in cases of completed carcinoma therapy, the survival rates in women who became subsequently pregnant and stood through the entire period of gestation, are distinctly improved. There is no medical indication for an abortion. A eugenic indication may be present especially in early pregnancy, if percutaneous subsequent irradiation and adjuvant chemotherapy are considered necessary. A social or psycho-social indication can be present if the individual prognosis and situation of the patient in question is taken into consideration. The decision becomes particularly difficult if the carcinoma is diagnosed during the second half of the period of gestation. In that case, prognosis deteriorates to the negative side. The fate as such, however, cannot be influenced by performing an abortion. To achieve viability of the child, adjuvant therapy must be delayed for a period of not longer than 12 weeks. Whether such a waiting period is justified or not, can only be decided from case to case by mutual consultation between the mother and the doctor.
基于过去40年发表的文献，讨论了医学、优生学以及社会或心理社会指征等问题。预后并不像通常认为的那样不利，尤其是在哺乳期。妊娠过程对预后没有明显可识别的不利影响。相反，在完成癌症治疗的病例中，随后怀孕并经历整个妊娠期的女性的生存率明显提高。没有医学上的堕胎指征。如果认为有必要进行经皮后续放疗和辅助化疗，尤其是在妊娠早期，可能存在优生学指征。如果考虑到患者的个体预后和情况，可能存在社会或心理社会指征。如果在妊娠期后半期诊断出癌症，决策会变得特别困难。在这种情况下，预后会向负面恶化。然而，堕胎并不能影响这样的命运。为了使胎儿能够存活，辅助治疗必须推迟不超过12周。这样的等待期是否合理，只能由母亲和医生逐案共同协商决定。
