Hodgkinson R, Husain F J
Anesth Analg. 1981 Jun;60(6):421-4.
Epidural anesthesia was administered for cesarean section in 250 patients using 20 ml of 0.75% bupivacaine administered at L3-4 with the patient in a sitting position for 5 minutes. Comparing the results with those obtained in a previous study in which parturients were kept horizontal at all times, it was found that the sitting position limited cephalad spread of anesthesia only in obese patients and that the decrease in spread was in proportion to the degree of obesity. The previous findings that cephalad spread is positively correlated to body mass index BMI (weight in kilograms divided by height in meters squared) and with body weight were confirmed.
对250例行剖宫产术的患者实施硬膜外麻醉，采用20毫升0.75%布比卡因于L3 - 4间隙给药，患者取坐位5分钟。将结果与之前一项研究（该研究中产妇全程保持平卧位）的结果进行比较，发现坐位仅在肥胖患者中限制了麻醉药向头侧扩散，且扩散减少程度与肥胖程度成正比。之前关于向头侧扩散与体重指数BMI（体重千克数除以身高米数的平方）以及体重呈正相关的研究结果得到了证实。
