Staudach A
Z Geburtshilfe Perinatol. 1981 Apr;185(2):84-8.
303 imminent premature deliveries were treated from 1977 to 1978 with hexoprenaline (Gynipral) on an inpatient basis. Indication for tocolysis was obtained according to the tocolysis index (Baumgarten). Cases with an index of three and more were evaluated only. This criterion enabled accurate separation between prophylactic and therapeutic tocolysis. By means of postpartal determination of the age of gestation via the Dubowitz score, the period of gestation was controlled which had been determined at the beginning of the tocolysis. This made it possible to detect erroneous indication due to false estimation of the gestation period. Tocolysis success was assessed according to two different aspects. Pharmacodynamic success was assumed if 15 or more points were attained according to the Weidinger success score. This occurred in 56,5% of all treated patients. Clinical success, defined by delivery of a child which did not die perinatally nor suffered from the respiratory distress syndrome, was seen in 90.7% of all treated patients.
1977年至1978年,303例即将早产的孕妇在住院期间接受了海索那林(Gynipral)治疗。根据宫缩抑制指数(鲍姆加滕)确定宫缩抑制的指征。仅对指数为3及以上的病例进行评估。该标准能够准确区分预防性宫缩抑制和治疗性宫缩抑制。通过产后根据杜波维茨评分确定孕周,对宫缩抑制开始时确定的孕周进行了对照。这使得能够检测出由于孕周估计错误导致的指征错误。从两个不同方面评估宫缩抑制的成功率。根据魏丁格成功评分达到15分或更多,则认为药物动力学成功。所有接受治疗的患者中有56.5%出现这种情况。临床成功定义为分娩的婴儿在围产期未死亡且未患呼吸窘迫综合征,所有接受治疗的患者中有90.7%出现临床成功。