Pene F, Avedian V, Eschwege F, Barrett A, Schwaab G, Marandas P, Vandenbrouck C
Cancer. 1978 Nov;42(5):2490-3. doi: 10.1002/1097-0142(197811)42:5<2490::aid-cncr2820420553>3.0.co;2-5.
Between 1958 and 1973, 131 patients with carcinoma of the posterior pharyngeal wall were treated at the Institute Gustave-Roussy (127 men, 4 women, mean age 61 years). Nine had a tumor of the oropharynx, 37 of the hypopharynx and 85 of the oro-hypopharynx. Nine had T1 tumors, 19 T2 and 103 T3 (TNM-UICC 1975). 122 patients were treated by irradiation: 83% were T3 lesions, 81% were more than 4 cm in diameter, 80% were ulcerated and 42% were staged N3. The survival rate of these patients was very poor (3% at five years). The nine patients who had been treated by surgical excision had a better survival rate and three are alive at 5 years, but the initial prognostic factors were better in this group. It seems that the indications for surgery should be widened to increase the survival rate in these poor prognosis cancers.
1958年至1973年间，古斯塔夫 - 鲁西研究所共治疗了131例下咽后壁癌患者（男性127例，女性4例，平均年龄61岁）。其中9例为口咽肿瘤，37例为下咽肿瘤，85例为口咽 - 下咽肿瘤。9例为T1期肿瘤，19例为T2期，103例为T3期（TNM - UICC 1975分期）。122例患者接受了放射治疗：其中83%为T3期病变，81%直径超过4厘米，80%有溃疡，42%为N3期。这些患者的生存率非常低（五年生存率为3%）。接受手术切除的9例患者生存率较好，5年后有3例存活，但该组患者的初始预后因素较好。似乎应扩大手术适应症，以提高这些预后不良癌症的生存率。
