Pyke K W, Bach J F
Thymus. 1981 Jun;3(1):1-7.
An in vitro migration system demonstrated the presence in murine fetal tissues of cells that migrate to thymus, spleen or lymph node. Preincubation of these cells with facteur thymique sérique, a factor derived from the thymus, produced changes in the migration patterns, suggesting a maturation sequence in fetal hemopoietic precursor-cell migration capacity, with migration to the thymus as the initial potential homing target, followed in order by a potential to migrate to the spleen, than to lymph-node tissue.
