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肠道异尖线虫病。一例病例报告及从市售鱼类中检出幼虫

Intestinal anisakiasis. Report of a case and recovery of larvae from market fish.

作者信息

Valdiserri R O

出版信息

Am J Clin Pathol. 1981 Sep;76(3):329-33. doi: 10.1093/ajcp/76.3.329.

Abstract

Intestinal anisakiasis refers to the accidental infection of humans by a marine nematode as a result of eating raw fish which contains larval stages of the nematode sub-family Anisakinae. The symptoms mimic appendicitis or regional enteritis and most cases are diagnosed post-operatively. This patient developed acute intestinal symptoms two weeks after eating raw salmon. A degenerating 150 micron larva accompanied by acute inflammation and granulation tissue was found in an adhesive band which extended from her jejunum to her omentum. Examination of a single salmon obtained from the same market where the patient shopped resulted in the recovery of 5 viable larvae, and confirmed the impression that anisakine infection of market fish is common. A related species (Phocanema) causes infestation, but not symptomatic disease. Although common in countries where raw fish is routinely eaten (e.g., Japan), its frequency is not proportional to the size of the group at risk, suggesting that predisposing factors influence the course of exposure. Preventative measures include freezing at -17 degrees for 24 hours.

摘要

肠道异尖线虫病是指人类因食用含有异尖线虫亚科幼虫阶段的生鱼而意外感染海洋线虫。其症状类似阑尾炎或局限性肠炎,大多数病例在术后确诊。该患者在食用生三文鱼两周后出现急性肠道症状。在一条从空肠延伸至大网膜的粘连带中发现了一条正在退化的150微米长的幼虫,伴有急性炎症和肉芽组织。对从患者购买三文鱼的同一市场获取的一条三文鱼进行检查,发现了5条活幼虫,证实了市场上的鱼感染异尖线虫很常见这一印象。一种相关物种(海豹线虫属)会引起感染,但不会引发症状性疾病。虽然在经常食用生鱼的国家(如日本)很常见,但其发病率与高危人群规模不成正比,这表明易感因素会影响接触后的发病过程。预防措施包括在-17摄氏度下冷冻24小时。

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