Giulling E V, Nikol'skiĭ I S, Kravchuk G P, Ovsienko V V, Khaloimova I L
Ontogenez. 1981;12(1):100-2.
The content of thymic serum factor in mice during the early postnatal ontogenesis is at the level characteristic of immunologically mature animals. Their spleen rosette-forming cells are, however, much less sensitive to antilymphocytic serum than those of adult animals. The sensitivity to the latter did not increase after incubation of splenocytes with thymosin or upon its multiple introduction to the neonatal mice. The results obtained suggest the refractoriness of the spleen rosette-forming cells to the thymic hormones during early postnatal ontogenesis.
出生后早期发育阶段小鼠胸腺血清因子的含量处于免疫成熟动物的特征水平。然而，它们的脾玫瑰花结形成细胞对抗淋巴细胞血清的敏感性远低于成年动物。将脾细胞与胸腺素一起孵育或多次给新生小鼠注射胸腺素后，对后者的敏感性并未增加。所获得的结果表明，出生后早期发育阶段脾玫瑰花结形成细胞对胸腺激素不敏感。
