[Blood coagulating and fibrinolytic activity of the endometrium in precancer and cancer].

The hemocoagulative and fibrinolytic characteristics of the endometrium in 16 cases with precancerous lesions and 16 cases of endometrial carcinoma were studied. The latter revealed an enhanced thromboplastic and antiheparin activity matched by a decrease in anticoagulative and fibrinolytic activity. It is suggested that uterine bleeding is due in such cases to local intravascular blood clotting, secondary activation of fibrinolysis and lysis of resultant clots.