Pleet A B, Massey E W, Vengrow M E
Neurology. 1981 Dec;31(12):1540-2. doi: 10.1212/wnl.31.12.1540.
Congenital bicuspid aortic valve, one of the most common congenital heart abnormalities, may become infected, may calcify, and may cause progressive stenosis or progressive insufficiency. While no previous reports suggested cerebral emboli in the absence of valvular infection, we studied four such cases. In all, cerebral angiography was normal and no extracardiac source of emboli was demonstrated. Microthrombus formation and valvular thickening with incompetence could eventuate in embolization.
先天性二叶式主动脉瓣是最常见的先天性心脏异常之一,可能会受到感染、发生钙化,并可能导致进行性狭窄或进行性关闭不全。虽然以前没有报告表明在没有瓣膜感染的情况下会出现脑栓塞,但我们研究了4例此类病例。总体而言,脑血管造影正常,未发现心外栓子来源。微血栓形成以及瓣膜增厚伴功能不全可能最终导致栓塞。