Scotti T M, Chernoff N, Linder R, McElroy W K
Toxicol Lett. 1981 Nov;9(3):289-94. doi: 10.1016/0378-4274(81)90163-6.
The early histologic lesions and sequential changes in the development of mirex-induced cataracts were studied in the offspring of lactating female Sherman rats given oral doses of mirex for 5 consecutive days post partum. The earliest histologic change, seen at neonatal day 7, was slight swelling of the individual cortical lens fibers. At day 9, many swollen but intact fibers were observed, and at days 11 and 13, extensive degeneration and necrosis appeared throughout the cortex of the affected lenses.
在产后连续5天经口给予泌乳期雌性谢尔曼大鼠灭蚁灵后，对其后代进行了研究，观察灭蚁灵诱发白内障的早期组织学病变及发育过程中的系列变化。最早的组织学变化见于出生后第7天，表现为单个皮质晶状体纤维轻度肿胀。在第9天，观察到许多肿胀但完整的纤维，在第11天和第13天，受影响晶状体的整个皮质出现广泛的变性和坏死。
