Filley C M, Graff-Richard N R, Lacy J R, Heitner M A, Earnest M P
Neurology. 1982 Mar;32(3):308-11. doi: 10.1212/wnl.32.3.308.
A young woman presented with podophyllin intoxication following topical application of podophyllin resin to genital condylomata acuminata. The disorder was marked by hallucinatory psychosis, bone marrow depression, and mild hepatic dysfunction. The psychosis and systemic disturbances resolved within 3 weeks, but were followed by autonomic and sensorimotor peripheral neuropathy. This case illustrates the transient central neurotoxicity and persistent peripheral neurotoxicity of podophyllin.
一名年轻女性在将鬼臼树脂局部应用于尖锐湿疣后出现鬼臼毒素中毒。该病症的特征为幻觉性精神病、骨髓抑制和轻度肝功能障碍。精神病和全身紊乱在3周内消退，但随后出现自主神经和感觉运动性周围神经病变。此病例说明了鬼臼毒素的短暂中枢神经毒性和持续周围神经毒性。
