Busse E, Rose H
Z Exp Chir. 1981;14(5):306-9.
Rats were differently treated after transplantation of cells of Jensen sarcoma to test the influence of Doparkin (increase of the cAMP level), morbilli vaccine (interferon inductor) and local radio-therapy alone or in combination for a decrease of the rate of growing tumors. The lowest rate of growing tumors was received by combining the agents with a local radio-therapy. The analysis of the thymic factor level showed in the animals with a tumor a significant reduction in comparison to normal animals respectively to animals without tumor formation in consequence of the therapy. An application of the thymic factor alone respectively in combination with Doparkin and morbilli vaccine leads to a clear decrease of the rate of growing tumors.
将詹森肉瘤细胞移植后，对大鼠进行不同处理，以测试多帕金（提高环磷酸腺苷水平）、麻疹疫苗（干扰素诱导剂）和局部放疗单独或联合使用对降低肿瘤生长速度的影响。联合使用这些药物并进行局部放疗时，肿瘤生长速度最低。胸腺因子水平分析表明，与正常动物相比，患肿瘤动物的胸腺因子水平显著降低，这是由于治疗导致未形成肿瘤的动物与正常动物相比也出现了这种情况。单独应用胸腺因子或与多帕金和麻疹疫苗联合应用，可明显降低肿瘤生长速度。
