Sipilä P
Acta Otolaryngol. 1982;93(1-6):243-50.
Proliferating cells in 148 mucoid middle ear effusions and corresponding blood samples of patients with secretory otitis media (SOM) were determined using the [3H]thymidine autoradiography technique. The blood specimens of SOM patients showed increased proportion of proliferating lymphocytes as compared to the control subjects. 60.1% of the effusions contained proliferating cells, but the proportion of proliferating cells depended on the viability of the cell population in the effusion. The blood specimens contained proliferating lymphocytes only, but the effusions contained proliferating lymphocytes and macrophages. The findings further suggest that SOM is an inflammatory disease involving an immune response to a specific antigen.
采用[3H]胸腺嘧啶核苷放射自显影技术，测定了148例分泌性中耳炎（SOM）患者黏液性中耳积液及相应血液样本中的增殖细胞。与对照组相比，SOM患者血液标本中增殖淋巴细胞的比例增加。60.1%的积液含有增殖细胞，但增殖细胞的比例取决于积液中细胞群体的活力。血液标本仅含有增殖淋巴细胞，而积液中含有增殖淋巴细胞和巨噬细胞。这些发现进一步表明，SOM是一种涉及对特定抗原免疫反应的炎症性疾病。
