Sipilä P, Karma P
Acta Otolaryngol. 1982 Nov-Dec;94(5-6):467-72. doi: 10.3109/00016488209128936.
Inflammatory cells were studied in 269 mucoid middle ear effusions of 202 patients with secretory otitis media (SOM). Although the effusions contained inflammatory cells in all cases, the number of cells, the proportion of viable cells and the proportions of different cell types showed marked heterogeneity. However, the effusions formed a sliding scale with regard to the above cellular parameters. We suggest that these differences in the cellular picture might reflect differences in immune mechanisms and responses in the different effusions, possibly representing different phases of the course of an established SOM. In the subgroups of patients with cleft palate (22) or atopy (16) the cellular picture resembled that seen in the other patients (164), with the exception that the effusions of the cleft palate patients were somewhat more lymphocytic. Thus, from the immunological point of view, the effusions in established SOM seem to behave similarly, irrespective of the differences in the etiological background of SOM.
对202例分泌性中耳炎（SOM）患者的269份黏液性中耳积液中的炎性细胞进行了研究。尽管所有病例的积液中均含有炎性细胞，但细胞数量、活细胞比例以及不同细胞类型的比例存在显著异质性。然而，就上述细胞参数而言，积液形成了一个连续变化的范围。我们认为，细胞图像的这些差异可能反映了不同积液中免疫机制和反应的差异，可能代表了已确诊SOM病程的不同阶段。在腭裂患者（22例）或特应性患者（16例）亚组中，细胞图像与其他患者（164例）相似，不同之处在于腭裂患者的积液淋巴细胞略多。因此，从免疫学角度来看，已确诊SOM的积液似乎表现相似，无论SOM病因背景存在何种差异。
