大鼠在遭受不可逃避或可逃避电击后的肿瘤排斥反应。
Tumor rejection in rats after inescapable or escapable shock.
作者信息
Visintainer M A, Volpicelli J R, Seligman M E
出版信息
Science. 1982 Apr 23;216(4544):437-9. doi: 10.1126/science.7200261.
PMID:7200261
Abstract
Rats experienced inescapable, escapable, or no electric shock 1 day after being implanted with a Walker 256 tumor preparation. Only 27 percent of the rats receiving inescapable shock rejected the tumor, whereas 63 percent of the rats receiving escapable shock and 54 percent of the rats receiving no shock rejected the tumor. These results imply that lack of control over stressors reduces tumor rejection and decreases survival.
摘要
在植入沃克256肿瘤制剂1天后，大鼠经历了不可逃避的电击、可逃避的电击或无电击。接受不可逃避电击的大鼠中只有27%排斥肿瘤，而接受可逃避电击的大鼠中有63%以及未接受电击的大鼠中有54%排斥肿瘤。这些结果表明，对压力源缺乏控制会降低肿瘤排斥反应并减少存活率。
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