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压力和应对因素会影响肿瘤生长。

Stress and coping factors influence tumor growth.

作者信息

Sklar L S, Anisman H

出版信息

Science. 1979 Aug 3;205(4405):513-5. doi: 10.1126/science.109924.

DOI:10.1126/science.109924
PMID:109924
Abstract

Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated as a result of various stress regimens. A single session of inescapable shock resulted in earlier tumor appearance, exaggeration of tumor size, and decreased survival time in recipient animals. Escapable shock had no such effects. The effects of the inescapable shock were mitigated if mice received long-term shock treatment.

摘要

通过各种应激方案评估了同基因P815肥大细胞瘤在DBA/2J雄性小鼠体内的生长情况。单次不可逃避电击会导致受体动物体内肿瘤出现更早、肿瘤大小增大以及存活时间缩短。可逃避电击则没有此类影响。如果小鼠接受长期电击处理,不可逃避电击的影响会减轻。

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