Ortiz J M, Eagle R C
Am J Ophthalmol. 1982 Mar;93(3):307-11. doi: 10.1016/0002-9394(82)90530-x.
Human babesiosis (Nantucket fever) is a rare, tick-borne intraerythrocytic parasitic disease characterized by fever, lymphadenopathy, arthralgias, and hemolytic anemia. A 34-year-old woman, who had previously undergone surgical removal of her spleen, was hospitalized because of presumed hepatitis. The many retinal nerve fiber layer infarcts and serologic abnormalities suggested collagen disease. The diagnosis of babesiosis was established by the demonstration of intraerythrocytic parasites and a greatly elevated titer to Babesia microti. The infection was treated with chloroquine, orally administered quinine, and pyramethamine, and her symptoms resolved within one month. The retinopathy was probably the result of focal vasculitis secondary to immune complex disease caused by chronic infection.
人类巴贝斯虫病（楠塔基特热）是一种罕见的、由蜱传播的红细胞内寄生虫病，其特征为发热、淋巴结病、关节痛和溶血性贫血。一名34岁的女性，此前已接受脾脏手术切除，因疑似肝炎而住院。多处视网膜神经纤维层梗死和血清学异常提示胶原病。通过在红细胞内发现寄生虫以及针对微小巴贝斯虫的滴度大幅升高确诊为巴贝斯虫病。感染采用氯喹、口服奎宁和乙胺嘧啶进行治疗，她的症状在一个月内得到缓解。视网膜病变可能是慢性感染引起的免疫复合物疾病继发局灶性血管炎的结果。
