Babichev V N, Ignatkov V Ia, Kofman I L, Pankov Iu A
Probl Endokrinol (Mosk). 1982 Mar-Apr;28(2):45-9.
In the experiments on rats the influence of the endogenic opioid beta-endorphine on the blood and hypophysis luteinizing hormone levels was studied after microiontophoretic injection of the hormone into diencephalon preoptic region. beta-Endorphine was shown to induce a significant decrease in blood hormone level and its increase in the hypophysis. No correlation was found between the changed hormone levels in the blood and hypophysis and beta-endorphine action. It is suggested that beta-endorphine participates in the mechanism, controlling luteinizing hormone release at the level of the cyclic center that regulates hypophyseal gonadotropic function.
在对大鼠的实验中，研究了在内源性阿片β-内啡肽经微离子电渗法注入间脑视前区后，其对血液和垂体促黄体生成素水平的影响。结果显示，β-内啡肽可使血液中激素水平显著降低，而垂体中激素水平升高。血液和垂体中激素水平的变化与β-内啡肽的作用之间未发现相关性。提示β-内啡肽参与了在调节垂体促性腺功能的周期性中枢水平上控制促黄体生成素释放的机制。
