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Protective effect of N-acetylcysteine on the urotoxicity produced by oxazaphosphorine without interference with anticancer activity.

作者信息

Morgan L R, Donley P J, Harrison E F, Hunter H L

出版信息

Eur J Cancer Clin Oncol. 1982 Jan;18(1):113-4. doi: 10.1016/0277-5379(82)90035-9.

DOI:10.1016/0277-5379(82)90035-9
PMID:7200891
Abstract
摘要

相似文献

1
Protective effect of N-acetylcysteine on the urotoxicity produced by oxazaphosphorine without interference with anticancer activity.N-乙酰半胱氨酸对氧氮磷杂环化合物所致尿毒性的保护作用，且不干扰其抗癌活性。
Eur J Cancer Clin Oncol. 1982 Jan;18(1):113-4. doi: 10.1016/0277-5379(82)90035-9.
2
The control of ifosfamide-induced hematuria with N-acetylcysteine in patients with advanced carcinoma of the lung.N-乙酰半胱氨酸对晚期肺癌患者异环磷酰胺诱导的血尿的控制作用
Semin Oncol. 1982 Dec;9(4 Suppl 1):71-4.
3
Phase I clinical study of acetylcysteine's preventing ifosfamide-induced hematuria.乙酰半胱氨酸预防异环磷酰胺所致血尿的I期临床研究
Semin Oncol. 1983 Mar;10(1 Suppl 1):62-5.
4
Prophylaxis of ifosfamide toxicity with oral acetylcysteine.口服乙酰半胱氨酸预防异环磷酰胺毒性
Semin Oncol. 1983 Mar;10(1 Suppl 1):66-71.
5
Cyclophosphamide and ifosfamide: role of uroprotective agents.
Cancer Invest. 1990;8(2):269. doi: 10.3109/07357909009017581.
6
The efficacy of mesna (2-mercaptoethane sodium sulfonate) as a uroprotectant in patients with hemorrhagic cystitis receiving further oxazaphosphorine chemotherapy.美司钠（2-巯基乙烷磺酸钠）作为尿路保护剂在接受进一步氮杂磷类化疗的出血性膀胱炎患者中的疗效。
J Clin Oncol. 1987 May;5(5):799-803. doi: 10.1200/JCO.1987.5.5.799.
7
N-acetylcysteine and ifosfamide in the treatment of unresectable pancreatic adenocarcinoma and refractory testicular cancer.N-乙酰半胱氨酸与异环磷酰胺治疗不可切除性胰腺腺癌和难治性睾丸癌
Semin Oncol. 1983 Mar;10(1 Suppl 1):72-5.
8
Pilot study of intravenous ifosfamide plus oral acetylcysteine in the treatment of non-small cell lung cancer.静脉注射异环磷酰胺联合口服乙酰半胱氨酸治疗非小细胞肺癌的初步研究
Vet Hum Toxicol. 1981;23(Suppl 1):12-4.
9
[High-dose ifosfamide therapy: systemic use of a mucolytic agent for the reduction of urotoxicity].[大剂量异环磷酰胺疗法：全身使用黏液溶解剂以降低尿路毒性]
Schweiz Med Wochenschr. 1979 Dec 8;109(47):1885-7.
10
[Effects of mesna (2-mercaptoethane sodium sulfonate) in children with malignant disease receiving oxazaphosphorine chemotherapy].[美司钠（2-巯基乙烷磺酸钠）对接受氮杂磷类化疗的恶性疾病患儿的影响]
Gan To Kagaku Ryoho. 1990 Mar;17(3 Pt 1):403-6.

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Cisplatin-induced mitochondrial dysfunction is associated with impaired cognitive function in rats.顺铂诱导的线粒体功能障碍与大鼠认知功能受损有关。
Free Radic Biol Med. 2017 Jan;102:274-286. doi: 10.1016/j.freeradbiomed.2016.11.046. Epub 2016 Nov 28.
2
The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo.抗氧化剂 N-乙酰半胱氨酸可防止体外低氧环境下 HIF-1 的稳定，但不影响体内多种乳腺癌模型的肿瘤发生。
PLoS One. 2013 Jun 20;8(6):e66388. doi: 10.1371/journal.pone.0066388. Print 2013.
3
Systematic review: generating evidence-based guidelines on the concurrent use of dietary antioxidants and chemotherapy or radiotherapy.
系统评价：生成关于饮食抗氧化剂与化疗或放疗联合应用的循证指南。
Cancer Invest. 2011 Dec;29(10):655-67. doi: 10.3109/07357907.2011.626479.
4
VP 16 plus ifosfamide plus cisplatin as salvage therapy in refractory testicular cancer.
Cancer Chemother Pharmacol. 1986;18 Suppl 2:S45-50. doi: 10.1007/BF00647451.
5
Clinical pharmacokinetics of N-acetylcysteine.N-乙酰半胱氨酸的临床药代动力学
Clin Pharmacokinet. 1991 Feb;20(2):123-34. doi: 10.2165/00003088-199120020-00004.
6
Comparison of N-acetylcysteine and mesna as uroprotectors with ifosfamide combination chemotherapy in refractory germ cell tumors.N-乙酰半胱氨酸和美司钠作为尿路保护剂与异环磷酰胺联合化疗用于难治性生殖细胞肿瘤的比较。
Invest New Drugs. 1992 Aug;10(3):159-63. doi: 10.1007/BF00877240.