Wendler D
Gegenbaurs Morphol Jahrb. 1981;127(5):641-8.
The long-term development of the CNS and its fundamental processes represent the basis of the high sensitivity of neural structures also during postnatal phases of development. Successive teratological rows of the CNS can be produced by application of different teratogenic substances at different times of development. Different teratogenic agents produce different malformations at the same day of development. Each teratogenic substance cause agent specific effects. Histological methods reveal the changing sensitivity of neural structures after application of special teratogenic agents at different times of development.
中枢神经系统(CNS)的长期发育及其基本过程是神经结构在出生后发育阶段仍具有高敏感性的基础。在发育的不同时期应用不同的致畸物质,可以产生一系列连续的中枢神经系统致畸情况。在发育的同一天,不同的致畸剂会产生不同的畸形。每种致畸物质都会产生特定的作用效果。组织学方法揭示了在发育的不同时期应用特殊致畸剂后神经结构敏感性的变化。