[Influence of centrophenoxine on the effect of cyclophosphamide and chloramphenicol in teratological experiment].
作者信息
Neumann H J
出版信息
Z Gesamte Inn Med. 1977 Jan 15;32(2):59-63.
PMID:322402
Abstract
Cyclophosphamide and chloramphenicol underwent a teralogical test in the animal experiment. The prenatal changes in the application of cyclophosphamide reveal the cytostatic remedy as a strong teratogenic remedy, whereas chloramphenicol in the first place has an embryotoxic effect and only a weak teratogenic one. The possibility of an influence on the prenatal changes caused by cyclophosphamide and chloramphenicol was tried with centrophenoxin. Apart from the weight of the foetuses the induced changes remained without influence in cyclophosphamide, whereas in chloramphenicol even in increase of the toxic effect could be observed.
摘要
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