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[与大鼠生理状态相关的下丘脑促黄体生成素含量]

[Luteinizing hormone content in the hypothalamus in relation to the physiological status of rats].

作者信息

Krivosheev O G, Nabatchikova N A, Isachenkov V A, Veselova S P

出版信息

Vopr Med Khim. 1982 Jul-Aug;28(4):126-31.

PMID:7202285
Abstract

Content and relative concentration (per 1 mg of protein) of luteinizing hormone (LH) varied in rat hypothalamus depending on the animal sex and age. In hamster hypothalamuses the hormone content correlated with the state of sexual cycle; maximal content of LH was found during estrus. Content of LH in hypothalamus depend also on the effect of light (rhythmic illumination, permanent light or darkness, duration of the light effect). After gonadectomy content of LH was increased in hypothalamus of female rats within 60 days. Simultaneous hypophys- and ovariectomies increased the LH content in hypothalamus already within 14 days after the treatment. Whole-body perfusion of rats did not alter the LH content in hypothalamus. LH was found in the middle and posterior parts of hypothalamus, particularly, in arcuate nucleus, middle eminence and mammillary bodies.

摘要

促黄体生成素(LH)在下丘脑的含量及相对浓度(每1毫克蛋白质)因大鼠的性别和年龄而异。在仓鼠下丘脑中,该激素含量与性周期状态相关;发情期时促黄体生成素含量最高。下丘脑中促黄体生成素的含量还取决于光照的影响(节律性光照、持续光照或黑暗、光照影响的持续时间)。去势后60天内,雌性大鼠下丘脑中促黄体生成素的含量增加。垂体切除和卵巢切除同时进行,在治疗后14天内就会使下丘脑中促黄体生成素的含量增加。对大鼠进行全身灌注不会改变下丘脑中促黄体生成素的含量。在下丘脑的中部和后部发现了促黄体生成素,特别是在弓状核、正中隆起和乳头体中。

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