大鼠腹侧前列腺中脂肪酸和氨基酸合成柠檬酸的过程。
Citrate synthesis from fatty acids and amino acids in rat ventral prostate.
作者信息
Toghrol F, Franklin R B, Costello L C
出版信息
Enzyme. 1980;25(6):371-6. doi: 10.1159/000459284.
The source of the remarkably high citrate level of prostate was investigated in prostate fragments. L-Aspartate and alpha-keto-glutarate formed oxaloacetate through transamination. Neither pyruvate nor acetate was as effective as palmitate in increasing the citrate level. The result suggested that the source of citrate in rat ventral prostate is oxaloacetate from amino acid transamination and acetyl CoA from fatty acid oxidation. Furthermore, the result indicated that carbohydrates contribute little to citrate production in ventral prostate.
在前列腺组织碎片中研究了前列腺中柠檬酸盐水平异常高的来源。L-天冬氨酸和α-酮戊二酸通过转氨作用形成草酰乙酸。丙酮酸和乙酸在提高柠檬酸盐水平方面都不如棕榈酸有效。结果表明，大鼠腹侧前列腺中柠檬酸盐的来源是氨基酸转氨作用产生的草酰乙酸和脂肪酸氧化产生的乙酰辅酶A。此外，结果表明碳水化合物对腹侧前列腺中柠檬酸盐的产生贡献很小。
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