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用3-甲基胆蒽处理的南非多乳鼠(原称非洲姬鼠)腺胃类癌和腺癌

Carcinoids and adenocarcinoma of the glandular stomach in Praomys (Mastomys) natalensis treated with 3-methylcholanthrene.

作者信息

Randeria J D

出版信息

Gan. 1980 Apr;71(2):159-64.

PMID:7202913
Abstract

Carcinoids and adenocarcinoma of the glandular stomach, analogous to those in man, were found in the chemically treated and control groups of Praomys (Mastomys) natalensis. The tumors were similar to the ones occurring spontaneously in this unique species. Adenocarcinoma of the pyloric and antral regions developed irrespective of treatment but of the fundic region only in the chemically treated group.

摘要

在经化学处理的南非多乳鼠(原称南非囊鼠)组和对照组中,发现了与人类相似的腺胃类癌和腺癌。这些肿瘤与该独特物种中自发出现的肿瘤相似。幽门和胃窦区域的腺癌无论是否接受处理都会发生,但仅在经化学处理的组中,胃底区域出现了腺癌。

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