von Sommoggy S, Theisinger W, Fraunhofer B
Fortschr Med. 1981 Jan 15;99(1-2):13-21.
Bowel sounds have a close correlation to the bowel peristalsis. By analysing these sounds--using Heinkelmann's method--sounds can be expressed by objective and calculable figures. We compared the effect of ceruletide, a hormone, with the cholinesterase inhibitor neostigmine and the alpha-adrenergic blocking substance dihydroergotamine. One of the drugs was injected twice daily in patients following operations in the gastrointestinal tract starting on the 3rd and 4th p.o. day. A group of 10 patients received ceruletide in a dose of 0,3 micrograms/kg body weight and of 0,5 micrograms/kg body weight, another 10 neostigmine (0,5 mg per single dose) and 10 patients dihydroergotamine in a dose of 1 mg. Ceruletide proved to be superior to the other drugs in both groups. Its advantage is exciting an ordered propulsive peristalsis. In cases of prolonged postoperative bowel atony or paralysis ceruletide is a helpful drug. Severe side effects were not seen.
肠鸣音与肠道蠕动密切相关。通过使用海因克尔曼方法分析这些声音，声音可以用客观且可计算的数字来表示。我们比较了一种激素——蛙皮素，与胆碱酯酶抑制剂新斯的明以及α-肾上腺素能阻滞剂双氢麦角胺的效果。从术后口服第3天和第4天开始，对接受胃肠道手术的患者每日注射两次其中一种药物。一组10名患者接受剂量为0.3微克/千克体重和0.5微克/千克体重的蛙皮素，另外10名患者接受新斯的明（单次剂量0.5毫克），还有10名患者接受剂量为1毫克的双氢麦角胺。结果表明，在两组中蛙皮素均优于其他药物。其优势在于能激发有序的推进性蠕动。在术后肠道长期无张力或麻痹的情况下，蛙皮素是一种有用的药物。未观察到严重的副作用。
