Stanciu C, Frasin M, Bălan G, Stratan I, Carniciu S
Rev Med Chir Soc Med Nat Iasi. 1989 Apr-Jun;93(2):247-50.
The effects of ceruletide on jejunal motor activity were studied in seven patients with postoperative intestinal atony. Jejunal pressures were recorded by three perfused catheters with orifices spaced 5 cm apart, the proximal one being positioned 10 cm beyond the ligament of Treitz. Ceruletide (0.05 microgram/Kg i.v.) significantly (p less than 0.0001) increased the number and amplitude of jejunal contractions. The action of ceruletide was most obvious the first 15-minutes after administration, then its effect diminished progressively and ceased after 65-75 minutes. The adverse reactions of ceruletide were minimal and self-limiting.
研究了缩胆囊素对7例术后肠麻痹患者空肠运动活性的影响。通过三根相距5 cm开口的灌注导管记录空肠压力，近端导管位于屈氏韧带以远10 cm处。缩胆囊素（0.05微克/千克静脉注射）显著（p<0.0001）增加空肠收缩的次数和幅度。缩胆囊素的作用在给药后的前15分钟最为明显，然后其作用逐渐减弱，并在65 - 75分钟后消失。缩胆囊素的不良反应轻微且为自限性。
