Lee S H, Rengachary S S, Paramesh J
Hum Pathol. 1981 Jan;12(1):92-5. doi: 10.1016/s0046-8177(81)80247-x.
Although several primary pulmonary neoplasms containing striated muscle fibers have in the past been described as rhabdomyoma or rhabdomyosarcoma, it was not until 1939 that McDonald and Heather described the first acceptable case of this neoplasm. Since then 13 such cases have been reported in the world literature. Previously reported cases of the neoplasm are reviewed and the salient features described. The origin of the striated muscle fibers has been much debated. Some believe that they develop from myoblastic differentiation of primitive mesenchymal cells or metaplastic transformation of pleuripotential mesenchymal cells present in the bronchial walls and pulmonary interstitium, whereas others claim that they develop from misplaced striated muscle tissue from the pharyngeal or esophageal region. A case report of the pleomorphic type of primary pulmonary rhabdomyosarcoma with multiple hematogenous metastases is presented as well as a review of the literature with a discussion of the histogenesis.
尽管过去有几种含有横纹肌纤维的原发性肺肿瘤被描述为横纹肌瘤或横纹肌肉瘤，但直到1939年，麦克唐纳和希瑟才描述了首例可接受的该肿瘤病例。从那时起，世界文献中已报道了13例此类病例。对先前报道的该肿瘤病例进行了回顾，并描述了其显著特征。横纹肌纤维的起源一直备受争议。一些人认为它们由原始间充质细胞的成肌细胞分化或支气管壁和肺间质中存在的多能间充质细胞的化生转变而来，而另一些人则声称它们由来自咽或食管区域的错位横纹肌组织发展而来。本文报告了一例伴有多处血行转移的多形性原发性肺横纹肌肉瘤病例，并结合文献复习对其组织发生进行了讨论。
