细胞群体动力学的计算机模拟

Computer simulation of the dynamics of cell populations.

作者信息

Mariani L, Scalici R

出版信息

Int J Biomed Comput. 1981 Mar;12(2):139-47. doi: 10.1016/0020-7101(81)90004-0.

PMID:7203709

Abstract

A modified version of the program of Valleron and Friendel is presented for the computer simulation of growing populations of cells. The method effects a sizable reduction of the storage requirement and allows one to follow the growth and division of cell clones for a large number of generations. Moreover, it is particularly useful to simulate specific biological events assumed to occur in the cell under various hypotheses and to compare them. Examples of this are also given.

摘要

本文提出了Valleron和Friendel程序的一个修改版本，用于对细胞生长群体进行计算机模拟。该方法显著降低了存储需求，并允许人们跟踪细胞克隆在大量世代中的生长和分裂。此外，对于模拟在各种假设下细胞中假定发生的特定生物学事件并进行比较，该方法特别有用。文中还给出了相关示例。