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大鼠尿液中葡萄糖-6-磷酸脱氢酶活性。肾脏损伤后的变化(简短报告)

Glucose-6-phosphatase dehydrogenase activity in rat urine. Changes following kidney damage (short report).

作者信息

Raab W

出版信息

Int J Clin Pharmacol Ther Toxicol. 1981 Jan;19(1):9-10.

PMID:7203733
Abstract

In rat urine, G-6-PDH activity is regularly present. Following the administration of nephrotoxic substances (D-serine, tetrathionate), or after elicitation of vascular shock (hypoxic kidney damage), a statistically significant increase in urinary G-6-PDH activity occurs. The alterations in urinary G-6-PDH activity largely correspond to the changes in urinary AP activity which, in this study, was determined in all of the experiments.

摘要

在大鼠尿液中,经常存在葡萄糖-6-磷酸脱氢酶(G-6-PDH)活性。给予肾毒性物质(D-丝氨酸、连四硫酸盐)后,或引发血管休克(缺氧性肾损伤)后,尿中G-6-PDH活性出现统计学上的显著增加。尿中G-6-PDH活性的变化在很大程度上与尿碱性磷酸酶(AP)活性的变化相对应,在本研究的所有实验中均测定了尿碱性磷酸酶活性。

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