Frenk E
Hautarzt. 1980 Dec;31(12):639-43.
Cutaneous depigmentation due to adhesive plaster was observed in four patients. It occurred after an eczematous reaction, was irreversible and strictly limited to the contact area. There is evidence that the depigmentation was induced, at least in two patients, by the polyvinyl/rubber-plastic sheet of the adhesive plaster. Patch tests and animal experiments did not permit to identify the depigmenting component or contaminant of the plastic sheet. Light- and electron microscopy showed a complete disappearance of the epidermal melanocytes in the depigmented skin. During the first year after damage, they were mostly replaced by indeterminate cells. Later on the predominant basal non-keratinocytes of the epidermis were Langerhans cells.
在四名患者中观察到因贴膏导致的皮肤色素脱失。其发生于湿疹样反应之后，不可逆且严格局限于接触部位。有证据表明，至少在两名患者中，色素脱失是由贴膏的聚乙烯/橡胶塑料片引起的。斑贴试验和动物实验未能确定塑料片中的色素脱失成分或污染物。光镜和电镜显示色素脱失皮肤中表皮黑素细胞完全消失。损伤后的第一年，它们大多被不确定细胞取代。后来，表皮中主要的基底非角质形成细胞是朗格汉斯细胞。
