Rydevik B, Lundborg G, Bagge U
J Hand Surg Am. 1981 Jan;6(1):3-12. doi: 10.1016/s0363-5023(81)80003-2.
Compression applied to a peripheral nerve may easily interfere with intraneural blood flow. In the present experimental study, a vital microscopic technique was used to observe changes in intraneural microcirculation (intrafascicularly and extrafascicularly) when graded compression was applied to a rabbit's tibial nerve by a specially designed minicompression device. Interference with venular flow was observed already at a pressure of 20 to 30 mm Hg while arteriolar and intrafascicular capillary flow was impaired at about 40 to 50 mm Hg. At 60 to 80 mm Hg no blood flow could be observed in the nerve. Nerves observed 3 or 7 days after 2 hours of compression at 400 mm Hg showed no or very slow stagnant blood flow within the previously compressed segment. It is concluded that acute compression of nerve may cause persistent impairment of intraneural microcirculation due to mechanical injury to blood vessels.
对周围神经施加压迫很容易干扰神经内血流。在本实验研究中，使用一种活体显微镜技术来观察当通过专门设计的微型压迫装置对兔胫神经施加分级压迫时神经内微循环（束内和束外）的变化。在20至30毫米汞柱的压力下就已观察到静脉血流受到干扰，而在约40至50毫米汞柱时小动脉和束内毛细血管血流受损。在60至80毫米汞柱时，神经内未观察到血流。在400毫米汞柱下压迫2小时后3天或7天观察到的神经，在先前受压节段内未观察到血流或仅有非常缓慢的停滞血流。得出的结论是，神经的急性压迫可能由于血管的机械损伤而导致神经内微循环的持续损害。
