弗里德赖希共济失调的周围和中枢体感神经传导缺陷
Peripheral and central somatosensory nerve conduction defects in Friedreich's ataxia.
作者信息
Jones S J, Baraitser M, Halliday A M
出版信息
J Neurol Neurosurg Psychiatry. 1980 Jun;43(6):495-503. doi: 10.1136/jnnp.43.6.495.
Abstract
Somatosensory evoked potentials were recorded over the clavicle, cervical spine, mastoid processes and the hand area of the contralateral somatosensory cortex to median nerve stimulation in 22 cases of Friedreich's ataxia. There was a marked attenuation of the clavicular potential, but little evidence of delay of this or the major cervical component. A dispersed and delayed cortical response was therefore suggestive of slowed conduction in central pathways. The cortical response was shown to be mediated by peripheral fibres with normal conduction velocity between stimulation sites at the wrist and the elbow.
摘要
对22例弗里德赖希共济失调患者进行正中神经刺激，在锁骨、颈椎、乳突以及对侧体感皮层手部区域记录体感诱发电位。锁骨电位明显衰减，但该电位或主要颈部成分几乎没有延迟迹象。因此，分散且延迟的皮层反应提示中枢传导通路传导减慢。结果表明，皮层反应由腕部和肘部刺激部位之间传导速度正常的外周纤维介导。
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