Jefferson D, Neary D, Eames R A
J Neurol Sci. 1981 Jan;49(1):19-29. doi: 10.1016/0022-510x(81)90184-2.
In an autopsy study of the pathology of chronic subclinical nerve entrapment Renaut bodies showed a strong predilection for sites of nerve entrapment. They were present at these sites in 43 of 74 peripheral nerves but in none of the control sections of the same nerves. Renaut bodies were most frequently encountered in the median nerve at the wrist and in the lateral femoral cutaneous nerve at the inguinal ligament but were rarely seen in sections of the common peroneal nerve at the neck of the fibula. Renaut bodies were closely associated with thickened subperineurial capillaries, and, in successive transverse sections, they terminated in a fibrous mass of these thickened vessels. In several nerves Renaut bodies showed a similar orientation within adjacent fascicles, suggesting that mechanical factors were related to their pathogenesis; despite this finding there was no relationship between their numbers at entrapment sites and the presence of pathological changes in myelinated nerve fibres at the same level. These findings suggest that while mechanical factors are important in the pathogenesis of Renaut bodies there is no evidence to support the theory that these structures protect nerve fibres from mechanical stress.
在一项关于慢性亚临床神经卡压病理学的尸检研究中，勒诺体对神经卡压部位表现出强烈的偏好。在74条周围神经的43条神经的这些部位发现了勒诺体，但在相同神经的对照切片中均未发现。勒诺体最常出现在腕部的正中神经和腹股沟韧带处的股外侧皮神经中，但在腓骨小头处的腓总神经切片中很少见。勒诺体与增厚的神经束膜下毛细血管密切相关，在连续的横切面上，它们终止于这些增厚血管的纤维团块中。在几条神经中，勒诺体在相邻的神经束内显示出相似的方向，这表明机械因素与其发病机制有关；尽管有这一发现，但它们在卡压部位的数量与同一水平有髓神经纤维的病理变化之间并无关联。这些发现表明，虽然机械因素在勒诺体的发病机制中很重要，但没有证据支持这些结构能保护神经纤维免受机械应力的理论。
