Sarper R, Fajman W A, Tarcan Y A, Nixon D W
J Nucl Med. 1981 Apr;22(4):318-21.
The purpose of this study was to develop a method by which the sensitivity of radionuclide liver imaging for the detection of hepatic metastasis could be enhanced. Routine flow studies were performed before imaging by injecting the usual 2-3 mCl dose of Tc-99m sulfur colloid as a bolus and storing 30 2-sec images in a computer. With regions selected by light pen, curves were generated from the right lobe of the liver, the right kidney, and the descending aorta. The peak of the kidney curve was chosen as a marker to separate the arterial and venous phases on the liver curve. The average slopes of four points on the liver curve before this marker, and four after, were calculated and the ratio of the first slope to that of the second was defined as the arterialization index. In this study with 228 patients, the inclusion of this index raised the sensitivity from 85 to 100%.
本研究的目的是开发一种方法，以提高放射性核素肝脏显像检测肝转移的敏感性。在显像前进行常规血流研究，通过静脉推注通常2 - 3毫居里剂量的锝- 99m硫胶体，并在计算机中存储30帧2秒的图像。用光标选定感兴趣区域，生成肝脏右叶、右肾和降主动脉的曲线。选择肾曲线的峰值作为标记，以区分肝曲线的动脉相和静脉相。计算该标记之前和之后肝曲线上四个点的平均斜率，并将第一个斜率与第二个斜率之比定义为动脉化指数。在这项针对228例患者的研究中，纳入该指数后敏感性从85%提高到了100%。
