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急性小剂量肼苯哒嗪诱发的狼疮综合征(HILS)。

Acute low-dose hydralazine induced lupus syndrome (HILS).

作者信息

Chisholm J C

出版信息

J Natl Med Assoc. 1981 Mar;73(3):278-80.

Abstract

A case of acute hydralazine induced lupus syndrome is described. No case has previously been described in which a small daily dose and a small accumulation dose have evoked this syndrome in such a short period of time. A pertinent and selective review of this syndrome is presented. The need for awareness of this syndrome manifesting in a patient exposed to small doses of hydralazine for short periods of time is emphasized.

摘要

本文描述了一例急性肼屈嗪诱发的狼疮综合征病例。此前尚无小剂量每日给药及小累积剂量在如此短时间内诱发该综合征的病例报道。本文对该综合征进行了相关且有选择性的综述。强调了对于短期接触小剂量肼屈嗪的患者出现该综合征的认识需求。

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本文引用的文献

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Genetic variations in the acetylation of isoniazid and other drugs.异烟肼及其他药物乙酰化过程中的基因变异。
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Mayo Clin Proc. 1969 Sep;44(9):664-81.
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Hydralazine elimination in man.
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