Fiechtner J J, Simkin P A
JAMA. 1981 Apr 17;245(15):1533-6.
We have identified urate crystals in gouty synovial fluid in a spherulite form. Studies in vitro established these "beachball" structures as chemically identical to classic "needles" of monosodium urate monohydrate, the prime factor in gouty arthritis. Previously described in the 1890s by a German scientist, these structures have not been recognized by clinicians examining fluid from arthritic joints. We suggest an identification scheme for beach ball-like" structures in synovial fluid.
我们在痛风性滑液中发现了球粒状的尿酸盐结晶。体外研究证实，这些“沙滩球”结构在化学性质上与痛风性关节炎的主要因素——经典的一水合尿酸钠“针状物”相同。这些结构在19世纪90年代由一位德国科学家首次描述，但检查关节炎关节液的临床医生尚未认识到它们。我们提出了一种识别滑液中“沙滩球样”结构的方案。
