Antommattei O, Schumacher H R, Reginato A J, Clayburne G
J Rheumatol. 1984 Dec;11(6):741-4.
Crystals can be identified in synovial fluids (SF) in the absence of acute inflammation as well as during acute gouty arthritis. We examined gouty joint effusions to evaluate whether observable properties of the crystals correlate with the clinically detectable inflammation. Higher SF leukocyte counts and more crystal phagocytosis were confirmed during more severe arthritis. We found no differences between crystal sizes, numbers of shapes in severe versus mild inflammation. Some patients with severe acute gout had few crystals or only punctate birefringent fragments. Factors other than those we examined must affect the severity of the inflammatory response in gouty arthritis.
在没有急性炎症以及急性痛风性关节炎期间,均可在滑液(SF)中发现晶体。我们检查了痛风性关节积液,以评估晶体的可观察特性是否与临床可检测到的炎症相关。在更严重的关节炎期间,证实滑液白细胞计数更高且晶体吞噬作用更强。我们发现,在严重炎症与轻度炎症之间,晶体大小、形状数量并无差异。一些严重急性痛风患者的晶体很少,或仅有点状双折射碎片。除我们所检查的因素外,其他因素必定会影响痛风性关节炎炎症反应的严重程度。