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与酮尿性糖尿病中国仓鼠小肠相关的毛细血管基底膜增厚。

Capillary basement membrane thickening associated with the small intestine of the ketonuric diabetic Chinese hamster.

作者信息

Diani A R, Weaver E A, Gerritsen G C

出版信息

Lab Invest. 1981 Apr;44(4):388-91.

PMID:7206632
Abstract

Morphometric evaluation of intestinal capillary basement membranes demonstrated a significant thickening in those of ketonuric diabetic Chinese hamsters compared to age-matched nondiabetic controls. A highly significant correlation was found between increased capillary basement membrane thickness and progression of ketonuria. Age was also positively related to elevation in capillary basement membrane thickness of control and diabetic hamsters. Capillary basement membrane thickness of diabetic animals was not significantly related to a combination of progredient ketonuria and advance in age.

摘要

对肠道毛细血管基底膜的形态学评估显示,与年龄匹配的非糖尿病对照组相比,酮尿性糖尿病中国仓鼠的肠道毛细血管基底膜显著增厚。毛细血管基底膜厚度增加与酮尿进展之间存在高度显著的相关性。年龄与对照组和糖尿病仓鼠毛细血管基底膜厚度的升高也呈正相关。糖尿病动物的毛细血管基底膜厚度与进行性酮尿和年龄增长的组合无显著相关性。

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