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脑转移性黑色素瘤的手术与非手术治疗

Surgical versus nonsurgical management of metastatic melanoma of the brain.

作者信息

Fell D A, Leavens M E, McBride C M

出版信息

Neurosurgery. 1980 Sep;7(3):238-42. doi: 10.1227/00006123-198009000-00006.

DOI:10.1227/00006123-198009000-00006
PMID:7207741
Abstract

A retrospective analysis of 80 patients with cerebral metastases from melanoma revealed that 42 patients in whom the metastases were excised experienced a median survival of 5 months, in comparison with a 6-week median survival for 38 patients who were not operated upon. The same survival figures applied when comparing only patients with known Stage 4 disease at the time of diagnosis of the brain metastasis. The surgical mortality rate was 9.5% for the entire series and 5.4% for the 37 patients treated surgically since 1960.

摘要

对80例黑色素瘤脑转移患者的回顾性分析显示,42例接受转移灶切除的患者中位生存期为5个月,相比之下,38例未接受手术的患者中位生存期为6周。在仅比较脑转移诊断时已知为4期疾病的患者时,生存数据相同。整个系列的手术死亡率为9.5%,自1960年以来接受手术治疗的37例患者的手术死亡率为5.4%。

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引用本文的文献

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Outcomes After Curative Metastasectomy for Patients with Malignant Melanoma: A Systematic Review and Meta-analysis.根治性转移切除术治疗恶性黑色素瘤患者的结局:系统评价和荟萃分析。
Ann Surg Oncol. 2022 Jun;29(6):3709-3723. doi: 10.1245/s10434-022-11351-4. Epub 2022 Feb 6.
2
Surgical treatment of metastatic brain tumors.转移性脑肿瘤的外科治疗
J Neurooncol. 1996 Mar;27(3):269-77. doi: 10.1007/BF00165484.
3
Cranial irradiation after surgical excision of brain metastases in melanoma patients.黑色素瘤患者脑转移瘤手术切除后进行颅脑照射。
Ann Surg Oncol. 1996 Mar;3(2):118-23. doi: 10.1007/BF02305789.
4
Management of metastatic brain tumors.转移性脑肿瘤的管理
Ann Surg Oncol. 1994 Mar;1(2):169-78. doi: 10.1007/BF02303562.
5
Brain metastasis from melanoma.黑色素瘤脑转移
J Neurooncol. 1983;1(4):313-7. doi: 10.1007/BF00165714.
6
Surgery as palliative treatment for distant metastases of melanoma.手术作为黑色素瘤远处转移的姑息性治疗方法。
Ann Surg. 1986 Aug;204(2):181-5. doi: 10.1097/00000658-198608000-00013.