Gaide M S, Klose K J, Gavin W J, Schneiderman N, Robertson T W, Silbert M, Faletti M V
Pharmacol Biochem Behav. 1980 Dec;13(6):851-7. doi: 10.1016/0091-3057(80)90218-x.
In weight lifting and rowing, essentially the same groups of muscles contract in isometric (static) and isotonic (dynamic) fashion. To approximate the combined static-dynamic arm movements involved in rowing or lifting weights, four rhesus monkeys were trained to pull a T-bar and thereby avoid tail shock. Each animal received 8 daily test sessions in which loads (0.4, 0.8, 1.2, 1.6 kg), total pulls (3, 6, 9, 12 at a constant pull frequency, 0.5 Hz) and alternate sessions of pulling after injection of hexamethonium chloride (7 mg/kg) or saline were factorially combined. Our data indicate that heart rate in this model is primarily influenced by the duration of the dynamic exercise component (number of pulls) in this specific exercise task whereas both dynamic and static components affect systolic and diastolic blood pressure. After ganglionic blockade, heart rate and diastolic pressure do not change appreciably during T-bar pulling while the rise in systolic pressure is attenuated and varies primarily as a function of the static exercise component. The clinical implications of these experiments are discussed.
在举重和划船运动中，基本上相同的几组肌肉以等长（静态）和等张（动态）方式收缩。为了模拟划船或举重中静态和动态手臂运动的组合，训练了四只恒河猴拉动T形杆，从而避免尾部电击。每只动物每天接受8次测试，其中负荷（0.4、0.8、1.2、1.6千克）、总拉动次数（在恒定拉动频率0.5赫兹下为3、6、9、12次）以及注射氯化六甲铵（7毫克/千克）或生理盐水后交替进行拉动的测试进行了析因组合。我们的数据表明，在这个模型中，心率主要受此特定运动任务中动态运动成分的持续时间（拉动次数）影响，而动态和静态成分都会影响收缩压和舒张压。在神经节阻断后，拉动T形杆期间心率和舒张压没有明显变化，而收缩压的升高减弱，并且主要随静态运动成分而变化。讨论了这些实验的临床意义。
