Stadaas J O
Scand J Gastroenterol. 1980;15(7):799-804. doi: 10.3109/00365528009181533.
The intragastric pressure/volume relationship was recorded in six patients with duodenal ulcer to study gastric motility before and after proximal gastric vagotomy (PGV). Recordings were done preoperatively and 6 weeks and 1 year after surgery by means of a flaccid plastic bag in the stomach connected to a low-pressure transducer. The bag was filled and emptied stepwise with defined volumes to study responses in gastric basal pressure or tone and contractions. Significant increase in basal pressure and reduced strength of rhythmic contractions were found 6 weeks after the operation, indicating disturbance of the gastric reservoir in the corpus and fundus. These changes were still present 1 year later, but some reduction of the pressure/volume relation was seen. The study indicates that a small tendency to adaptation or a revere towards normal occurs with gastric motility responses to volume loads simulating a meal 1 year after PGV, but the changes are still significantly different from the preoperative recordings.
记录了6例十二指肠溃疡患者的胃内压力/容积关系，以研究近端胃迷走神经切断术（PGV）前后的胃动力。术前、术后6周和1年通过置于胃内的一个松弛塑料袋连接低压传感器进行记录。通过逐步向袋内注入和排空特定容积的液体来研究胃基础压力或张力及收缩的反应。术后6周发现基础压力显著升高，节律性收缩强度降低，提示胃体和胃底的胃储器功能紊乱。这些变化在1年后仍然存在，但压力/容积关系有所降低。该研究表明，PGV术后1年，胃对模拟进餐的容积负荷的动力反应有轻微的适应倾向或恢复正常的趋势，但变化仍与术前记录有显著差异。
