Rosenberg N J, Bargar W L, Friedman B
Spine (Phila Pa 1976). 1981 Jan-Feb;6(1):35-8. doi: 10.1097/00007632-198101000-00005.
Radiographs were obtained of the lumbosacral spines of 143 patients that had never walked. The frequency of spondylolysis and spondylolisthesis was determined, as well as that of other spinal abnormalities. The average age of the patients was 27 years, with a range of 11 to 93 years. The underlying diagnoses responsible for the nonambulatory status varied, but cerebral palsy predominated. No case of spondylolysis or spondylolisthesis was detected, and when compared to the 5.8% incidence in the general population, this finding is significant at the P less than 0.001 level. The incidences of spinal bifida (8.4%) and of transitional vertebrae (10.9%) are similar to those found in the general population. Scoliosis was found in 49% and vertebral body height was increased in 32.9%. Degenerative changes occurred in only 2.8%. These results support the theory that spondylolysis and isthmic spondylolisthesis represent a fatigue fracture resulting from activities associated with ambulation.
对143例从未行走的患者的腰骶椎进行了X线摄影。确定了椎弓根峡部裂和椎体滑脱的发生率以及其他脊柱异常的发生率。患者的平均年龄为27岁，范围为11至93岁。导致不能行走状态的潜在诊断各不相同，但以脑瘫为主。未检测到椎弓根峡部裂或椎体滑脱病例，与普通人群中5.8%的发生率相比，这一发现具有显著性（P<0.001）。脊柱裂（8.4%）和移行椎（10.9%）的发生率与普通人群中的发生率相似。发现49%的患者有脊柱侧弯，32.9%的患者椎体高度增加。仅2.8%的患者出现退行性改变。这些结果支持了这样一种理论，即椎弓根峡部裂和峡部性椎体滑脱是由与行走相关的活动导致的疲劳性骨折。
