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在两例绞窄性肠梗阻中使用吲哚菁绿荧光成像显示肠灌注。

Bowel perfusion demonstrated using indocyanine green fluorescence imaging in two cases of strangulated ileus.

机构信息

Department of Surgery, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

出版信息

Clin J Gastroenterol. 2022 Oct;15(5):886-889. doi: 10.1007/s12328-022-01656-y. Epub 2022 Jun 28.

DOI:10.1007/s12328-022-01656-y
PMID:35763151
Abstract

We report the use of indocyanine green (ICG) fluorescence for intraoperative diagnosis in two cases of strangulated ileus. We successfully preserved the bowel and avoided postoperative complications by detecting adequate perfusion and no necrosis in the intestine's strangulated regions. In the first case, enhanced computed tomography (CT) revealed a closed loop intestine, which showed poor contrast, and we performed laparotomy with ICG fluorescence. In the second case, the CT scan revealed bowel obstruction without ascites. We conservatively treated the patient with the insertion of a long tube. The patient's condition did not improve, and we performed laparotomy using ICG fluorescence. In both of these cases, the visual observation during laparotomy showed that the ileum had dark-red discoloration. We demonstrated perfusion and preserved the ileum by injecting 2.5 mg of ICG intravenously; fluorescence was observed in the dark-red ileum using the PINPOINT system (Novadaq, Kalamazoo, MI, US). Both patients recovered successfully after the surgery with no adverse events. Our data suggest that ICG fluorescence imaging can be one of the decision-making modalities in patients with strangulated ileus.

摘要

我们报告了在两例绞窄性肠梗阻中使用吲哚菁绿(ICG)荧光进行术中诊断的情况。我们通过检测肠绞窄区域的充分灌注和无坏死,成功保留了肠管并避免了术后并发症。在第一例中,增强 CT 显示闭襻肠,造影不佳,我们进行了剖腹手术并使用 ICG 荧光。在第二例中,CT 扫描显示肠梗阻而无腹水。我们采用插入长管进行保守治疗。患者病情未见改善,我们使用 ICG 荧光进行了剖腹手术。在这两种情况下,剖腹手术时的视觉观察显示回肠呈暗红色变色。我们通过静脉注射 2.5mg ICG 来证明灌注并保留了回肠;使用 PINPOINT 系统(Novadaq,Kalamazoo,MI,US)观察暗红色回肠的荧光。两名患者手术后均成功康复,无不良事件发生。我们的数据表明,ICG 荧光成像可以成为绞窄性肠梗阻患者的决策模式之一。

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引用本文的文献

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Utility of indocyanine green fluorescent dye in emergency general surgery: a review of the contemporary literature.吲哚菁绿荧光染料在急诊普通外科中的应用:当代文献综述
Front Surg. 2024 Feb 14;11:1345831. doi: 10.3389/fsurg.2024.1345831. eCollection 2024.
2
A Hypothetical New Challenging Use for Indocyanine Green Fluorescence during Laparoscopic Appendectomy: A Mini-Series of Our Experience and Literary Review.吲哚菁绿荧光在腹腔镜阑尾切除术中的一种假设性新挑战应用:我们的经验与文献综述小系列
J Clin Med. 2023 Aug 8;12(16):5173. doi: 10.3390/jcm12165173.
3
Usefulness of indocyanine green fluorescence-guided small intestinal bleeding site identification in small bowel resection: a report of two cases and literature review.

本文引用的文献

1
Fluorescence imaging visualizes three sets of regional lymph nodes in patients with lower rectal cancer.荧光成像可使低位直肠癌患者的三组区域淋巴结显影。
Hepatogastroenterology. 2012 Jul-Aug;59(117):1381-4. doi: 10.5754/hge11281.
2
Small bowel obstruction: the role of nonoperative treatment in simple intestinal obstruction and predictive criteria for strangulation obstruction.小肠梗阻:非手术治疗在单纯性肠梗阻中的作用及绞窄性肠梗阻的预测标准。
Surgery. 1981 Apr;89(4):407-13.
吲哚菁绿荧光引导下小肠出血部位识别在小肠切除术中的应用:两例报告及文献复习。
Clin J Gastroenterol. 2023 Jun;16(3):349-354. doi: 10.1007/s12328-023-01787-w. Epub 2023 Apr 12.