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心脏直视手术后的心肺并发症、呼吸治疗与动脉血氧分压(作者译)

[Cardio-pulmonary complications, respiratory treatment and PaO2 after open heart surgery (author's transl)].

作者信息

Gattiker R, Pescia R

出版信息

Herz. 1978 Jun;3(3):191-7.

PMID:721050
Abstract

Despite the almost complete disappearance of the so called "postperfusion lung syndrome" after cardiac surgery with extracorporeal circulation (ECC), there is still a need for respiratory treatment in some cases, primarily for cardio-circulatory or respiratory reasons. In addition postoperative artificial ventilation is provided routinely in many centers for at least a few hours, until stabilization of cardio-circulatory and metabolic state is achieved. In 4 groups (I-IV) with a total of 659 patients (18 to 72 years old) undergoing open cardiac surgery for acquired heart disease (I: aortic valve, II: mitral valve, III: multivalvular disease, IV: coronary artery disease) postoperative cardio-circulatory and pulmonary complication rate, duration of artificial ventilation needed, PaO2 and some influencing factors have been evaluated. Group II and III show the highest rate of complications, 15.5 and 19.8% respectively, versus 7.7 and 8.1% in group I and IV respectively. The mean duration of postoperative respiratory treatment in cases with complications within all groups (133--156 h) is about 6 times the duration of respiratory treatment in the non complicated cases (23--24 h). In all 4 groups mean PaO2 at the time of extubation is lower for the complicated compared with the non complicated cases. Age of patients, severity of disease, preoperative pulmonary function, prolonged duration of ECC and myocardial ischemia have been found to be predisposing factors for postoperative cardio-pulmonary complications, whereas the duration of anesthesia and the type of anesthesia do not show any influence.

摘要

尽管在体外循环(ECC)心脏手术后所谓的“灌注后肺综合征”几乎完全消失,但在某些情况下,仍需要进行呼吸治疗,主要是出于心血管循环或呼吸方面的原因。此外,许多中心常规进行术后人工通气至少几个小时,直到心血管循环和代谢状态稳定。对4组(I-IV)共659例(18至72岁)因后天性心脏病接受心脏直视手术的患者(I:主动脉瓣,II:二尖瓣,III:多瓣膜疾病,IV:冠状动脉疾病)的术后心血管循环和肺部并发症发生率、所需人工通气时间、动脉血氧分压(PaO2)及一些影响因素进行了评估。II组和III组的并发症发生率最高,分别为15.5%和19.8%,而I组和IV组分别为7.7%和8.1%。所有组中出现并发症的病例术后呼吸治疗的平均时间(133 - 156小时)约为无并发症病例(23 - 24小时)呼吸治疗时间的6倍。在所有4组中,与无并发症病例相比,并发症病例拔管时的平均动脉血氧分压较低。已发现患者年龄、疾病严重程度、术前肺功能、体外循环时间延长和心肌缺血是术后心肺并发症的易感因素,而麻醉时间和麻醉类型未显示出任何影响。

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