Missal O, Schulz G, Jachmann M
Z Erkr Atmungsorgane. 1980;155(1):140-4.
In 180 patients with histologically confirmed bronchial carcinoma exactitude of aldolase as a means for carrying out a screening test for metastases and relapses was checked. Enzyme activity was mostly normal in patients with limited extended local tumor growth including regional metastases as well as in tumour relapses. The group of patients with distant metastases, showed a distribution of increases and normal enzyme values which was equal; when differentiating further the majority of pathological aldolase values (79.4 per cent) was found in the group with liver metastases. We therefore regard as valuable the determination of serum aldolase when locking for liver metastases in confirmed bronchial carcinoma.
对180例经组织学确诊的支气管癌患者,检查了醛缩酶作为转移和复发筛查手段的准确性。在局部肿瘤生长受限包括区域转移以及肿瘤复发的患者中,酶活性大多正常。远处转移患者组中,酶值升高和正常的分布情况相同;进一步区分时,大多数病理性醛缩酶值(79.4%)出现在肝转移组。因此,我们认为在确诊的支气管癌中寻找肝转移时,测定血清醛缩酶是有价值的。